Prescription medicines
Approved prescription medicines have reviewed labeling, defined active ingredients and strengths, contraindications, and manufacturing requirements.
Dietary supplements
Supplements do not go through the same premarket approval process for treating disease. Product quality and evidence can vary.
Hidden ingredients
Some products marketed for sexual enhancement have been found to contain undeclared sildenafil-like substances, creating dangerous nitrate interactions.
How to shop more safely
Avoid disease-treatment claims, verify the seller and manufacturer, review FDA warnings, and discuss ingredients with a clinician or pharmacist.
Imported sildenafil and tadalafil are prescription drugs, not supplements
Direct-purchase imported brands have different approval, supply-chain, and legal questions from dietary supplements. Review them in the separate imported-medication library.
Open imported medication reviewsHow to use this comparison
- Identify the treatment category and care model you actually want.
- Normalize dose strength, quantity, refill interval, and every recurring fee.
- Read the current provider terms and pharmacy information.
- Give the clinician a complete health and medication history.
- Stop and seek urgent care for warning symptoms described in the prescribing information.